I think it would look nice, but considering pleco fish are nocturnal, it might disturb them. Im not a fish expert so Im unsure.
Based on experience with the epoxy coated gravel, I have to agree with Tifftastic. Every colored gravel I've ever had ends up peeling within 3 months, which is why I paid a bit more for the CaribSea sand for my 180g.
In regards to the question of neon gravel, a lot of it is now marketed for GloFish tanks - IF said fish are legal in your location. The neon colors "glow" under the blue lights that come in the GloFish aquarium kits. And yes, it does look pretty cool.
Petsmart/Petco house brands. Aesthetically I prefer a dark substrate, which is why I now use black sand. I have found it easier to work with. My sister prefers gravel, so it's in her tanks. She has a GloFish tank.
Back in the day of undergravel filters, I used gravel. The colored stuff would end up peeling, so I started using natural colors. It's also epoxy coated, but since it's clear epoxy over natural colors, it's next it impossible to tell if the coating is peeling. When I used black gravel, the coating would come off faster due to vigorous stirring of the gravel in order to remove the accumulated debris.